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Peptides / GHK-Cu / United States

GHK-Cu in the United States

Legal status, what it is, and the listed suppliers in the United States that list it.

Legal status in the United States

Not an approved medicine. Used as a cosmetic ingredient.

As understood at 2026-09-22. Verify with the FDA.

What GHK-Cu is

GHK-Cu is a naturally occurring three-amino-acid peptide bound to copper. It is found in human plasma, saliva and urine, and its concentration declines with age. It is long-established as a cosmetic skincare ingredient, which makes it unusual among the substances on this site.

Full GHK-Cu page: targets and research →

Listed suppliers in the United States

9 of the 10 suppliers we list in the United States list GHK-Cu. Listed, not endorsed: each row is the supplier’s own stated terms.

BioLongevity Labs United States All products are manufactured for research use only. Research Use Only products sold here are intended solely for laboratory research. Core Peptides United States Products are for laboratory, research or analytical purposes only, and are not for human consumption. Direct Peptides United States All products are sold strictly for laboratory research use only and are not for human or animal consumption. Direct Peptides is a chemical supplier, not a compounding pharmacy or 503A/503B facility. HEEZ Research United States All products are for laboratory developmental research use only. Products are not for human consumption. HEEZ Research is a chemical supplier. Licensed Peptides United States Supplied strictly for laboratory research use only. Not intended for human consumption, veterinary use, therapeutic applications, or diagnostic use. No dosing instructions are provided. Nationwide Peptides United States For Research Use Only. Products are not intended for human or animal consumption, ingestion, injection, or any form of administration. Peak Lab Peptides United States All products on this site are for research and development use only. Products are not for human consumption of any kind. Protide Health United States All products are supplied for laboratory research only and are not for human or animal consumption, medical use, veterinary use, or any therapeutic, diagnostic, or clinical purpose. Sigma Compounds United States Products are for research and development purposes only and are not for human consumption.

Clinical Research

In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ in rat experimental wounds
Maquart FX, Bellon G, Chaqour B, et al. (1993). Journal of Clinical Investigation. animal rats with wound chambers implanted under the skin, given repeated injections of GHK-Cu or saline
Regenerative and protective actions of the GHK-Cu peptide in the light of the new gene data
Pickart L, Margolina A (2018). International Journal of Molecular Sciences. review n/a (review)
Middle-aged mice treated with GHK-Cu peptide administered intraperitoneally or intranasally show behavioral rescue but divergent hippocampal aging programs
Mazzola J, Rosenfeld M, Tucker M, Wezeman J, Ladiges W, Liao GY (2026). bioRxiv (preprint). preprint aged C57BL/6J mice (20–21 months), both sexes