Peptides / KPV / United Kingdom

KPV in the United Kingdom

Legal status, what it is, and the listed suppliers in the United Kingdom that list it.

Legal status in the United Kingdom

Not an approved medicine.

As understood at 2026-09-22. Verify with the MHRA.

What KPV is

KPV is a three-amino-acid peptide (lysine-proline-valine) that corresponds to the tail end of alpha-melanocyte-stimulating hormone, a hormone involved in pigmentation and in damping inflammation. It is made synthetically. The published research is preclinical: cell culture, mice and rabbits.

Full KPV page: targets and research →

Clinical Research

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation
Dalmasso G, Charrier-Hisamuddin L, Nguyen HTT, et al. (2008). Gastroenterology. animal human intestinal epithelial and T cell lines, plus mice in two colitis models (DSS and TNBS)
Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease
Kannengiesser K, Maaser C, Heidemann J, et al. (2008). Inflammatory Bowel Diseases. animal mice, two colitis models (DSS colitis and CD45RB-high transfer colitis), plus mice carrying a non-functional melanocortin-1 receptor
Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
Xiao B, Xu Z, Viennois E, et al. (2017). Molecular Therapy. animal cultured intestinal cells and macrophages, then mice with induced ulcerative colitis
Effects of the COOH-terminal tripeptide alpha-MSH(11-13) on corneal epithelial wound healing: role of nitric oxide
Bonfiglio V, Camillieri G, Avitabile T, et al. (2006). Experimental Eye Research. animal rabbits with surgically abraded corneal epithelium in both eyes, plus cultured rabbit corneal epithelial cells