Thymosin β4: actin-sequestering protein moonlights to repair injured tissues
Goldstein AL, Hannappel E, Kleinman HK (2005). Trends in Molecular Medicine.
Summary
A review of thymosin beta-4, the full protein from which TB-500 is derived. Summarises its known role in binding actin inside cells and collects animal-model evidence for effects on wound healing, cell migration and cardiac tissue after injury. Concerns the whole protein; findings may not transfer directly to the TB-500 fragment.