Clinical Research

Randomized controlled trial of oral glutathione supplementation on body stores of glutathione

Richie JP, Nichenametla S, Neidig W, et al. (2015). European Journal of Nutrition.

Summary

Asked whether swallowing glutathione raises the body's own stores of it, which had been shown in animals but not in people. Fifty-four non-smoking adults took one of two oral amounts or placebo for six months, with glutathione measured in blood, red cells, plasma, lymphocytes and cheek cells. Levels rose at one, three and six months at both amounts; by six months the higher-intake group was up by roughly a third in red cells, plasma and lymphocytes and far more in cheek cells, while the lower-intake group rose in blood and red cells. The study measures body stores, not health outcomes.