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Peptides / FOXO4-DRI / United Kingdom

FOXO4-DRI in the United Kingdom

Legal status, what it is, and the listed suppliers in the United Kingdom that list it.

Legal status in the United Kingdom

Not an approved medicine.

As understood at 2026-09-22. Verify with the MHRA.

What FOXO4-DRI is

FOXO4-DRI is a synthetic peptide designed in 2017 by a group at Erasmus MC in the Netherlands to kill senescent cells, the damaged cells that stop dividing but accumulate with age. It copies a stretch of the FOXO4 protein but is built from D-amino acids in reverse order, which makes it resistant to breakdown, and carries a cell-penetrating tag. It is a research compound; no human trials have been published.

Full FOXO4-DRI page: targets and research →

Listed suppliers in the United Kingdom

1 of the 10 suppliers we list in the United Kingdom list FOXO4-DRI. Listed, not endorsed: each row is the supplier’s own stated terms.

XL Peptides United Kingdom All products are exclusively sold for research purposes. They are not intended for human use, therapeutic, diagnostic, or clinical application.

Clinical Research

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
Baar MP, Brandt RMC, Putavet DA, et al. (2017). Cell. animal cultured senescent cells; fast-ageing (XpdTTD/TTD) and naturally aged mice
FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice
Zhang C, Xie Y, Chen H, et al. (2020). Aging. animal senescent TM3 Leydig cells in culture; naturally aged mice
FOXO4-DRI regulates endothelial cell senescence via the P53 signaling pathway
Hu Z, Li F, Hu C, et al. (2026). Frontiers in Bioengineering and Biotechnology. animal naturally aged and progeroid mice; cultured endothelial cells under oxygen-glucose deprivation
Senolytic Peptide FOXO4-DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes
Huang Y, He Y, Makarcyzk MJ, Lin H (2021). Frontiers in Bioengineering and Biotechnology. in-vitro human cartilage cells from healthy donors, expanded in culture