Peptides / KPV / United States

KPV in the United States

Legal status, what it is, and the listed suppliers in the United States that list it.

Legal status in the United States

Not an approved medicine.

As understood at 2026-09-22. Verify with the FDA.

What KPV is

KPV is a three-amino-acid peptide (lysine-proline-valine) that corresponds to the tail end of alpha-melanocyte-stimulating hormone, a hormone involved in pigmentation and in damping inflammation. It is made synthetically. The published research is preclinical: cell culture, mice and rabbits.

Full KPV page: targets and research →

Listed suppliers in the United States

10 of the 10 suppliers we list in the United States list KPV. Listed, not endorsed: each row is the supplier’s own stated terms.

American Peptides United States Products are sold for Research Use Only and not for Human Consumption. Not for human or veterinary use. BioLongevity Labs United States All products are manufactured for research use only. Research Use Only products sold here are intended solely for laboratory research. Core Peptides United States Products are for laboratory, research or analytical purposes only, and are not for human consumption. Direct Peptides United States All products are sold strictly for laboratory research use only and are not for human or animal consumption. Direct Peptides is a chemical supplier, not a compounding pharmacy or 503A/503B facility. HEEZ Research United States All products are for laboratory developmental research use only. Products are not for human consumption. HEEZ Research is a chemical supplier. Licensed Peptides United States Supplied strictly for laboratory research use only. Not intended for human consumption, veterinary use, therapeutic applications, or diagnostic use. No dosing instructions are provided. Nationwide Peptides United States For Research Use Only. Products are not intended for human or animal consumption, ingestion, injection, or any form of administration. Peak Lab Peptides United States All products on this site are for research and development use only. Products are not for human consumption of any kind. Protide Health United States All products are supplied for laboratory research only and are not for human or animal consumption, medical use, veterinary use, or any therapeutic, diagnostic, or clinical purpose. Sigma Compounds United States Products are for research and development purposes only and are not for human consumption.

Clinical Research

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation
Dalmasso G, Charrier-Hisamuddin L, Nguyen HTT, et al. (2008). Gastroenterology. animal human intestinal epithelial and T cell lines, plus mice in two colitis models (DSS and TNBS)
Melanocortin-derived tripeptide KPV has anti-inflammatory potential in murine models of inflammatory bowel disease
Kannengiesser K, Maaser C, Heidemann J, et al. (2008). Inflammatory Bowel Diseases. animal mice, two colitis models (DSS colitis and CD45RB-high transfer colitis), plus mice carrying a non-functional melanocortin-1 receptor
Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
Xiao B, Xu Z, Viennois E, et al. (2017). Molecular Therapy. animal cultured intestinal cells and macrophages, then mice with induced ulcerative colitis
Effects of the COOH-terminal tripeptide alpha-MSH(11-13) on corneal epithelial wound healing: role of nitric oxide
Bonfiglio V, Camillieri G, Avitabile T, et al. (2006). Experimental Eye Research. animal rabbits with surgically abraded corneal epithelium in both eyes, plus cultured rabbit corneal epithelial cells