Peptides / NAD+ / United Kingdom

NAD+ in the United Kingdom

Legal status, what it is, and the listed suppliers in the United Kingdom that list it.

Legal status in the United Kingdom

Not an approved medicine.

As understood at 2026-09-22. Verify with the MHRA.

What NAD+ is

NAD+ is not a peptide. It is a coenzyme built from two nucleotides, present in every living cell, where it carries electrons in the reactions that release energy from food. It has a page here because it is the single most widely stocked product across the listings in this directory. Levels fall with age, which is the premise behind selling it.

Full NAD+ page: targets and research →

Clinical Research

NAD+ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence
Gallagher C, Emmanuel OO (2026). Ageing Research Reviews. review n/a (113 studies: 33 human intervention studies, 28 of them randomised, and 80 rodent studies, 2010 to 2025)
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Martens CR, Denman BA, Mazzo MR, et al. (2018). Nature Communications. human healthy middle-aged and older adults, randomised double-blind placebo-controlled crossover, two 6-week periods
Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial
Norheim KL, Ben Ezra M, Heckenbach I, et al. (2024). Nature Aging. human 40 patients with stable COPD; randomised, double-blind, placebo-controlled, 6 weeks of treatment with follow-up 12 weeks later
A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment
Orr ME, Kotkowski E, Ramirez P, et al. (2023). GeroScience. human 20 older adults with mild cognitive impairment; randomised placebo-controlled pilot, 10 weeks