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Peptides / NAD+ / United States

NAD+ in the United States

Legal status, what it is, and the listed suppliers in the United States that list it.

Legal status in the United States

Not an approved medicine.

As understood at 2026-09-22. Verify with the FDA.

What NAD+ is

NAD+ is not a peptide. It is a coenzyme built from two nucleotides, present in every living cell, where it carries electrons in the reactions that release energy from food. It has a page here because it is the single most widely stocked product across the listings in this directory. Levels fall with age, which is the premise behind selling it.

Full NAD+ page: targets and research →

Listed suppliers in the United States

10 of the 10 suppliers we list in the United States list NAD+. Listed, not endorsed: each row is the supplier’s own stated terms.

American Peptides United States Products are sold for Research Use Only and not for Human Consumption. Not for human or veterinary use. BioLongevity Labs United States All products are manufactured for research use only. Research Use Only products sold here are intended solely for laboratory research. Core Peptides United States Products are for laboratory, research or analytical purposes only, and are not for human consumption. Direct Peptides United States All products are sold strictly for laboratory research use only and are not for human or animal consumption. Direct Peptides is a chemical supplier, not a compounding pharmacy or 503A/503B facility. HEEZ Research United States All products are for laboratory developmental research use only. Products are not for human consumption. HEEZ Research is a chemical supplier. Licensed Peptides United States Supplied strictly for laboratory research use only. Not intended for human consumption, veterinary use, therapeutic applications, or diagnostic use. No dosing instructions are provided. Nationwide Peptides United States For Research Use Only. Products are not intended for human or animal consumption, ingestion, injection, or any form of administration. Peak Lab Peptides United States All products on this site are for research and development use only. Products are not for human consumption of any kind. Protide Health United States All products are supplied for laboratory research only and are not for human or animal consumption, medical use, veterinary use, or any therapeutic, diagnostic, or clinical purpose. Sigma Compounds United States Products are for research and development purposes only and are not for human consumption.

Clinical Research

NAD+ supplementation for anti-aging and wellness: A PRISMA-guided systematic review of preclinical and clinical evidence
Gallagher C, Emmanuel OO (2026). Ageing Research Reviews. review n/a (113 studies: 33 human intervention studies, 28 of them randomised, and 80 rodent studies, 2010 to 2025)
Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults
Martens CR, Denman BA, Mazzo MR, et al. (2018). Nature Communications. human healthy middle-aged and older adults, randomised double-blind placebo-controlled crossover, two 6-week periods
Effect of nicotinamide riboside on airway inflammation in COPD: a randomized, placebo-controlled trial
Norheim KL, Ben Ezra M, Heckenbach I, et al. (2024). Nature Aging. human 40 patients with stable COPD; randomised, double-blind, placebo-controlled, 6 weeks of treatment with follow-up 12 weeks later
A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment
Orr ME, Kotkowski E, Ramirez P, et al. (2023). GeroScience. human 20 older adults with mild cognitive impairment; randomised placebo-controlled pilot, 10 weeks