SLU-PP-332 | peptidefix

Summary

SLU-PP-332 is a synthetic small molecule, not a peptide. It is an agonist of the estrogen-related receptors (ERR alpha, beta and gamma), a family of nuclear receptors involved in mitochondrial and oxidative metabolism gene programmes, and was made as a research tool compound. It has a page here because several listed suppliers sell it alongside their peptides.

What it targets

ERR agonists act on gene programmes linked to mitochondrial function and oxidative metabolism in muscle. In the one study linked below, muscle biopsies were taken from 20 women during hip replacement surgery and split by self-reported physical activity; myoblasts cultured from the less active group were then treated with SLU-PP-332, which was associated with reversal of the observed expression differences (NOX4, SIRT1, PGC-1 alpha, ERR alpha, FNDC5), less oxidative stress and senescence, and more myotube formation. The compound was applied to cells in culture, not given to people. No human trial of SLU-PP-332 appears in the literature reviewed for this page.

mitochondrial and oxidative metabolism gene expression (in vitro)markers of age-related muscle atrophy in cultured myoblasts

Clinical Research

Targeting ERRs to counteract age-related muscle atrophy associated with physical inactivity: a pilot study

Bonanni R, Falvino A, Matticari A, et al. (2025). Frontiers in Physiology. in-vitro muscle biopsies from 20 women undergoing hip replacement (10 active, 10 inactive); primary myoblasts from the inactive group treated in culture

All research on SLU-PP-332 →

Suppliers stocking SLU-PP-332

5 of the 30 listed suppliers. Each row opens its full listing.

Aussie Peptides Australia Research use only. Statements have not been evaluated by the TGA. We do not ship internationally at this time. Australian Peptide Site Australia Intended for laboratory and scientific research use only. Nationwide Peptides United States For Research Use Only. Products are not intended for human or animal consumption, ingestion, injection, or any form of administration. Peak Lab Peptides United States All products on this site are for research and development use only. Products are not for human consumption of any kind. XL Peptides United Kingdom All products are exclusively sold for research purposes. They are not intended for human use, therapeutic, diagnostic, or clinical application.