Peptide Directory

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Most-studied peptides

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Ranked by published human clinical trials on PubMed, with completed trials registered on ClinicalTrials.gov alongside. A count of research, not a measure of how well anything works.

  1. 1
    Semaglutide

    Studied for body weight in overweight and obesity (phase 3)

    339 published
    348 completed registered trials
    UKApproved medicine
    USApproved medicine
    AUPrescription only
  2. 2
    Tirzepatide

    Studied for body weight in obesity (phase 3, 2,539 people)

    145 published
    89 completed registered trials
    UKApproved medicine
    USApproved medicine
    AUPrescription only
  3. 3
    Thymosin alpha-1

    Studied for sepsis (phase 3, 1,106 people, no significant benefit)

    86 published
    24 completed registered trials
    UKNot approved
    USNot approved
    AUNot approved
  4. 4
    Glutathione

    Studied for raising the body's glutathione stores (randomised, 54 adults)

    65 published
    32 completed registered trials
    UKNot approved
    USNot approved
    AUPrescription only
  5. 5
    Sermorelin

    Studied for growth hormone deficiency in children (randomised, 43 children)

    53 published
    11 completed registered trials
    UKNot approved
    USNo FDA label
    AUPrescription only
  6. 6
    NAD+

    Studied for raising NAD+ levels via oral precursors (systematic review and trials)

    Counts trials of the precursors nicotinamide riboside and NMN.

    46 published
    54 completed registered trials
    UKNot approved
    USNot approved
    AUNot approved
  7. 7
    VIP (vasoactive intestinal peptide)

    Studied for pulmonary hypertension (inhaled, n=20)

    38 published
    12 completed registered trials
    UKApproved medicine
    USNot approved
    AUPrescription only
  8. 8
    Tesamorelin

    Studied for visceral fat in HIV-associated lipodystrophy (human trials)

    23 published
    13 completed registered trials
    UKNot approved
    USApproved medicine
    AUPrescription only
  9. 9
    SS-31 (elamipretide)

    Studied for Barth syndrome (open-label extension, n=10; case report)

    14 published
    21 completed registered trials
    UKNot approved
    USApproved medicine
    AUNot approved
  10. 10
    Cagrilintide

    Studied for body weight with semaglutide (two phase 3 trials)

    13 published
    23 completed registered trials
    UKNot approved
    USNot approved
    AUNot approved
Sources: PubMed (clinical trials and randomised controlled trials) and ClinicalTrials.gov (completed studies). Ties go to registered trials. Updated Monday and Thursday.Counts as of 26 Oct 2026

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