peptidefix

Tesamorelin

Also: Egrifta, Egrifta SV, GHRH(1-44) analogue

Growth hormone axisMetabolic & weight
Legal status United KingdomNot approvedUnited StatesApproved medicineAustraliaPrescription only
Research on peptidefix

5 papers: 5 human studies.

Listed suppliers United Kingdom10United States11Australia7 Europe7
Checked 2026-11-03

Legal status as understood on this date. Listed, not endorsed. How we list.

Summary

Tesamorelin is a synthetic, stabilised analogue of growth hormone-releasing hormone, the hypothalamic hormone that prompts the pituitary to release growth hormone. Unlike most substances covered on this site it is an approved medicine in the United States, sold as Egrifta, for one specific indication.

What it targets

Tesamorelin acts on the growth hormone axis and raises IGF-1. Its clinical programme was in people with HIV on antiretroviral therapy who had accumulated visceral fat. In a 404-person randomised double-blind trial, visceral adipose tissue fell by about 11 percent over six months against under 1 percent on placebo, reaching about 18 percent in those who continued for a year, with the reduction rapidly lost when treatment was switched to placebo and no change in limb or subcutaneous abdominal fat. A later 50-person trial found liver fat fell as well. A 12-week trial in 53 people with type 2 diabetes, run because growth hormone can worsen insulin sensitivity, found no significant change in insulin response or glycaemic control. A 2025 phase 2 trial found no clear improvement in neurocognitive performance despite a greater reduction in waist circumference.

visceral fat in HIV-associated lipodystrophy (human trials)liver fat in people with HIV and abdominal fat accumulationglucose control and insulin response (safety trial)neurocognitive performance in people with HIV (no significant effect)

Clinical Research

Body composition, hepatic fat, metabolic, and safety outcomes of tesamorelin in HIV-associated lipodystrophy: a meta-analysis of randomized controlled trials
Badran AS, Helal A, Shata KS, Ayesh H (2026). Obesity Research & Clinical Practice. meta-analysis 5 randomised placebo-controlled trials in adults with HIV
Effects of Tesamorelin, a Growth Hormone-Releasing Factor, in HIV-Infected Patients With Abdominal Fat Accumulation: A Randomized Placebo-Controlled Trial With a Safety Extension
Falutz J, Potvin D, Mamputu JC, et al. (2010). JAIDS Journal of Acquired Immune Deficiency Syndromes. human 404 people with HIV on antiretroviral therapy with excess abdominal fat, randomised, double-blind, 12 months
Effect of Tesamorelin on Visceral Fat and Liver Fat in HIV-Infected Patients With Abdominal Fat Accumulation: A Randomized Clinical Trial
Stanley TL, Feldpausch MN, Oh J, et al. (2014). JAMA. human 50 people with HIV on antiretroviral therapy with abdominal fat accumulation, randomised, double-blind, placebo-controlled, 6 months
Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial
Clemmons DR, Miller S, Mamputu JC (2017). PLOS ONE. human 53 people with type 2 diabetes, randomised to placebo or one of two tesamorelin groups, 12 weeks
Effects of Tesamorelin on Neurocognitive Impairment in Persons With HIV and Abdominal Obesity
Ellis RJ, Vaida F, Hu K, et al. (2025). The Journal of Infectious Diseases. human 73 people with HIV, virally suppressed, with abdominal obesity; phase 2, randomised, open-label against standard of care, 6 months

All research on Tesamorelin →

Suppliers stocking Tesamorelin

35 of the 49 listed suppliers. Each row opens its full listing.

Au Peptide Labs Australia For laboratory research use only. Not for human consumption. Aussie Peptides Australia Research use only. Statements have not been evaluated by the TGA. We do not ship internationally at this time. Australian Peptide Site Australia Intended for laboratory and scientific research use only. Australian Research Peptides Australia All products sold by Australian Research Peptides are supplied for in vitro research purposes only — not for human or animal consumption, and not drugs, foods, cosmetics or dietary supplements. Baltic BioLabs Lithuania For laboratory research only, not for human or veterinary use. Baltic Peptides Lithuania All products are supplied strictly for laboratory research use only. Not for human or veterinary use. BioLongevity Labs United States All products are manufactured for research use only. Research Use Only products sold here are intended solely for laboratory research. Bluewell Peptides United Kingdom All Bluewell products are supplied strictly for laboratory research use only. They are not intended for human consumption, medical use, therapeutic use, diagnostic use, or veterinary use. British Peptide Labs United Kingdom For research use only. Not for human or veterinary use. Sold strictly for in-vitro laboratory research; not for diagnosis or treatment. Core Peptides United States Products are for laboratory, research or analytical purposes only, and are not for human consumption. Direct Peptides United States All products are sold strictly for laboratory research use only and are not for human or animal consumption. Direct Peptides is a chemical supplier, not a compounding pharmacy or 503A/503B facility. Dutch Peptides Netherlands Research Use Only — not for human consumption. Eurolabs Peptides Germany For research purposes only. Not for human consumption. Global Peptides Australia Unmodified peptides are sold for research use only. HEEZ Research United States All products are for laboratory developmental research use only. Products are not for human consumption. HEEZ Research is a chemical supplier. Licensed Peptides United States Supplied strictly for laboratory research use only. Not intended for human consumption, veterinary use, therapeutic applications, or diagnostic use. No dosing instructions are provided. Midshire Labs United Kingdom All Midshire Labs products are sold strictly for research purposes only. They are not intended for human consumption, medical, veterinary, or diagnostic use. Nationwide Peptides United States For Research Use Only. Products are not intended for human or animal consumption, ingestion, injection, or any form of administration. Next Gen Peptides Australia Not for human consumption. Novacell Peptides Estonia All products of NCBL Sciences OÜ / NovaCell Peptides are intended exclusively for laboratory-based in-vitro research. Not for human or veterinary use, not a medicinal product, food or cosmetic. Peak Lab Peptides United States All products on this site are for research and development use only. Products are not for human consumption of any kind. Peptides Lab UK United Kingdom Strictly intended for laboratory research use only. Not for human or veterinary consumption. Prism Labs United States All products sold by Prism Labs are intended strictly for in-vitro research, laboratory experimentation, and educational purposes. Products are not intended for human or veterinary use. Protide Health United States All products are supplied for laboratory research only and are not for human or animal consumption, medical use, veterinary use, or any therapeutic, diagnostic, or clinical purpose. Pulse Peptides Cyprus Products are not intended for administration to humans or animals and are not presented as having any medical, diagnostic, therapeutic, or clinical purpose. Pure Peptides UK United Kingdom All products are for research use only. Research Peptide United Kingdom Supplied strictly for research and laboratory use only and not for human or veterinary consumption. Research Peptides Europe Ireland Lyophilised peptides are for research / laboratory use only — not for human use. Sigma Compounds United States Products are for research and development purposes only and are not for human consumption. Stratford Peptides United Kingdom Products sold are for research purposes only and are not for human or veterinary use. Synapse Peptides Australia Australia All products are supplied strictly for research purposes only and are not intended for human or veterinary use. The Peptide Company United Kingdom Supplied strictly for laboratory research purposes only. Not intended for human consumption, medical use or self-administration. ThePeptideCode United Kingdom All products on this website are supplied strictly as research materials for laboratory and research use only — not for human or veterinary use. UK Peptides United Kingdom All products are sold exclusively for in-vitro research. They are not for human or veterinary use. Xeno Peptides United States All products are for laboratory and research use only — not for human consumption or clinical application.