GHK-Cu delays aging in Caenorhabditis elegans via coordinated regulation of mitochondrial function and activation of DAF-16/SKN-1 pathways
Wen H, Zhao K, Luo X, et al. (2026). Biogerontology.
Summary
A laboratory study in C. elegans roundworms testing GHK-Cu (the copper complex of the tripeptide GHK). GHK-Cu extended lifespan and improved several age-related measures, including stress resistance, movement and lipid accumulation. It also preserved mitochondrial function and activated the DAF-16 and SKN-1 pathways. The authors describe it as the first mechanistic evidence of this kind. The study was in worms, not people. No competing interests were declared.