Peptides / 5-amino-1MQ / United States

5-amino-1MQ in the United States

Legal status, what it is, and the listed suppliers in the United States that list it.

Legal status in the United States

Not an approved medicine.

As understood at 2026-09-22. Verify with the FDA.

What 5-amino-1MQ is

5-amino-1MQ is not a peptide. It is a small molecule that inhibits nicotinamide N-methyltransferase, an enzyme that sits between cellular metabolism and the regulation of gene activity. It is a research compound with no published human data at all, and it is on this site because listed suppliers sell it alongside peptides.

Full 5-amino-1MQ page: targets and research →

Clinical Research

Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction
Babula JJ, Bui D, Stevenson HL, et al. (2024). Diabetes, Obesity and Metabolism. animal diet-induced obese mice given the compound daily for 28 days, plus pharmacokinetic work after intravenous, oral and subcutaneous administration
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
Neelakantan H, Vance V, Wetzel MD, et al. (2018). Biochemical Pharmacology. animal cultured adipocytes and permeability assays, then mice made obese on a high-fat diet
A small molecule inhibitor of Nicotinamide N-methyltransferase for the treatment of metabolic disorders
Kannt A, Rajagopal S, Kadnur SV, et al. (2018). Scientific Reports. animal diet-induced obese mice, ob/ob and db/db mice, and NNMT knockout mice as a specificity control
Exploring NNMT: from metabolic pathways to therapeutic targets
Park J, Shin EJ, Kim TH, et al. (2024). Archives of Pharmacal Research. review n/a (review)