peptidefix

Pinealon

Also: Glu-Asp-Arg, EDR peptide

Cognitive
Legal status United KingdomNot approvedUnited StatesNot approvedAustraliaNot approved
Research on peptidefix

2 papers: 1 cell study, 1 review or preprint.

Listed suppliers United Kingdom3United States4Australia0 Europe5
Checked 2026-11-03

Legal status as understood on this date. Listed, not endorsed. How we list.

Summary

Pinealon is a synthetic three-amino-acid peptide (Glu-Asp-Arg) from the Khavinson series of bioregulator peptides. Its developers describe it as neuroprotective. The published literature is small, comes almost entirely from the developing institute, and does not include controlled human trials.

What it targets

In cultured rat neurons, neutrophils and PC12 cells under oxidative stress, Pinealon was associated with lower reactive-oxygen-species accumulation and less cell death, with changes to ERK signalling and the cell cycle. A 2021 review by the developers collects their cell and animal work and proposes a mechanism for Alzheimer's disease in which the peptide enters cells and alters gene expression; that mechanism is hypothesised, not demonstrated. The review mentions memory findings in elderly patients but the underlying trial is not among the papers linked here.

oxidative stress in cultured cellsneuroprotection mechanism (review, hypothesis)

Clinical Research

Pinealon Increases Cell Viability by Suppression of Free Radical Levels and Activating Proliferative Processes
Khavinson V, Ribakova Y, Kulebiakin K, et al. (2011). Rejuvenation Research. in-vitro rat cerebellar granule cells, neutrophils and PC12 cells in culture
EDR Peptide: Possible Mechanism of Gene Expression and Protein Synthesis Regulation Involved in the Pathogenesis of Alzheimer's Disease
Khavinson V, Linkova N, Kozhevnikova E, Trofimova S (2021). Molecules. review n/a (review)

All research on Pinealon →

Suppliers stocking Pinealon

12 of the 49 listed suppliers. Each row opens its full listing.

CertaPeptides Romania All CertaPeptides products are sold exclusively for in-vitro laboratory research. They are not approved for human consumption, veterinary use, therapeutic applications… Core Peptides United States Products are for laboratory, research or analytical purposes only, and are not for human consumption. Eurolabs Peptides Germany For research purposes only. Not for human consumption. Licensed Peptides United States Supplied strictly for laboratory research use only. Not intended for human consumption, veterinary use, therapeutic applications, or diagnostic use. No dosing instructions are provided. Midshire Labs United Kingdom All Midshire Labs products are sold strictly for research purposes only. They are not intended for human consumption, medical, veterinary, or diagnostic use. Nationwide Peptides United States For Research Use Only. Products are not intended for human or animal consumption, ingestion, injection, or any form of administration. Novacell Peptides Estonia All products of NCBL Sciences OÜ / NovaCell Peptides are intended exclusively for laboratory-based in-vitro research. Not for human or veterinary use, not a medicinal product, food or cosmetic. Nupex United Kingdom Products sold on nupex.co.uk are for research purposes only and are not for human or veterinary use. Particle Peptides Slovakia Goods offered by the Company in the E-shop for purposes of scientific research and development (in vitro). Protide Health United States All products are supplied for laboratory research only and are not for human or animal consumption, medical use, veterinary use, or any therapeutic, diagnostic, or clinical purpose. Research Peptides Europe Ireland Lyophilised peptides are for research / laboratory use only — not for human use. Tide Labs United Kingdom For laboratory research use only. Not for human or veterinary use.