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Peptides / Pancragen / United States

Pancragen in the United States

Legal status, what it is, and the listed suppliers in the United States that list it.

Legal status in the United States

Not an approved medicine.

As understood at 2026-09-22. Verify with the FDA.

What Pancragen is

Pancragen is a synthetic four-amino-acid peptide (Lys-Glu-Asp-Trp) from the Khavinson series of bioregulator peptides, designed from a peptide extract of pancreatic tissue. All published research is from the developing institute and none is in humans.

Full Pancragen page: targets and research →

Listed suppliers in the United States

None of the suppliers we list in the United States list Pancragen.

Clinical Research

Effect of pancragen on blood glucose level, capillary permeability and adhesion in rats with experimental diabetes mellitus
Khavinson VKh, Gavrisheva NA, Malinin VV, Chefu SG, Trofimov EL (2007). Bulletin of Experimental Biology and Medicine. animal Wistar rats with streptozotocin-induced diabetes
Correction of impaired glucose tolerance using tetrapeptide (Pancragen) in old female rhesus monkeys
Goncharova ND, Ivanova LG, Oganyan TE, Vengerin AA, Khavinson VK (2015). Advances in Gerontology (Uspekhi Gerontologii). animal old female rhesus monkeys (20–25 years), n=9 (5 pancragen, 4 glimepiride)
Effects of pancragen on the differentiation of pancreatic cells during their ageing
Khavinson VKh, Durnova AO, Polyakova VO, et al. (2013). Bulletin of Experimental Biology and Medicine. in-vitro 'young' and 'aged' pancreatic cell cultures
Study of biological activity of Lys-Glu-Asp-Trp-NH2 endogenous tetrapeptide
Khavinson VKh, Gapparov MM, Sharanova NE, Vasilyev AV, Ryzhak GA (2010). Bulletin of Experimental Biology and Medicine. animal rats during development and with streptozotocin-induced diabetes
Study of interactions between DNA and tetrapeptides using methods of molecular mechanics
Tarnovskaya SI, Yakutseni PP, Khavinson VKh (2014). Bulletin of Experimental Biology and Medicine. in-vitro computational molecular modelling; no cells or animals